Lexapro PMS (Escitalopram oxalate) is one of the medicines that doctors can prescribe to treat depression during PMS (premenstrual syndrome). Lexapro also treats PMS-associated anxiety. Lexapro is a selective serotonin re-uptake inhibitor (SSRI) and so belongs to the same family of medicines as Prozac/Sarafem and Zoloft, other drugs now routinely used to treat PMS/PMDD (premenstrual

